Title: errors-in-variables regression Long Title: IUPAC Gold Book - errors-in-variables regression DOI: 10.1351/goldbook.10150 Status: current Definition Least squares regression in which both the response variable and predictor variable have measurement error. Notes 1) The model for EIV regression is \[\left\{\matrix{c_{i} = \alpha + \beta x_{i}^{*} + \varepsilon_{i} \cr x_{i} = x_{i}^{*} + \eta_{i} \cr}\right.\] where \(x^{*}\) is the true value of the predictor variable, \(c_{i}\) concentration and \(\varepsilon\) and \(\eta\) are errors. 2) When the errors \(\varepsilon\) and \(\eta\) have the same variance the method is called orthogonal regression and minimises the perpendicular distance of a point to the regression line. 3) Total least squares regression is performed by singular value decomposition. Related Term - singular value decomposition: https://goldbook.iupac.org//terms/view/10115 Source - PAC, 2016, 88, 407. 'Vocabulary of concepts and terms in chemometrics (IUPAC Recommendations 2016)' on page 434 (https://doi.org/10.1515/pac-2015-0605) Other Outputs - html: https://goldbook.iupac.org/terms/view/10150/html - json: https://goldbook.iupac.org/terms/view/10150/json - xml: https://goldbook.iupac.org/terms/view/10150/xml Citation: Citation: 'errors-in-variables regression' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10150 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-07-24T05:18:16+00:00