Title: interaction effect Long Title: IUPAC Gold Book - interaction effect DOI: 10.1351/goldbook.10075 Status: current Definition Effect of a factor where the term is the product of two or more factors. Example The yield of a synthesis is modelled in terms of the temperature \(T\) and concentration of a reactant \(c\): \[\hat Y = {\hat \beta}_{0} + {\hat \beta}_{1}T + {\hat \beta}_{2}c + {\hat \beta}_{11}T^{2} + {\hat \beta}_{22}c^{2} + {\hat \beta}_{12}Tc\] The estimated coefficient \({\hat \beta}_{12}\) and is the interaction effect of \(T\) and \(c\) Related Terms - Effect of a factor: https://goldbook.iupac.org//terms/view/10068 - main effect: https://goldbook.iupac.org//terms/view/10076 - nth-order effect: https://goldbook.iupac.org//terms/view/10078 Source - PAC, 2016, 88, 407. 'Vocabulary of concepts and terms in chemometrics (IUPAC Recommendations 2016)' on page 415 (https://doi.org/10.1515/pac-2015-0605) Other Outputs - html: https://goldbook.iupac.org/terms/view/10075/html - json: https://goldbook.iupac.org/terms/view/10075/json - xml: https://goldbook.iupac.org/terms/view/10075/xml Citation: Citation: 'interaction effect' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10075 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-08-08T16:05:58+00:00