Title: relative molecular-mass exclusion limit
Long Title: IUPAC Gold Book - relative molecular-mass exclusion limit
DOI: 10.1351/goldbook.09965
Status: current

Definition
Maximum value of the relative molecular masses of components in a specific polymer solvent system that can enter into the pores of the porous non-adsorbing material used in size-exclusion chromatography.

Note
For particles with relative molar mass greater than the exclusion limit the separation effect of the size-exclusion chromatography vanishes.

Source
- PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 212 (https://doi.org/10.1515/pac-2017-0111)

Other Outputs
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- json: https://goldbook.iupac.org/terms/view/09965/json
- xml: https://goldbook.iupac.org/terms/view/09965/xml

Citation: Citation: 'relative molecular-mass exclusion limit' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09965
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Accessed: 2026-04-19T05:40:02+00:00