Title: pH-zone-refining counter-current chromatography Long Title: IUPAC Gold Book - pH-zone-refining counter-current chromatography DOI: 10.1351/goldbook.09947 Status: current Definition Counter-current chromatography that produces a train of fused rectangular solute peaks called pH-zones, each with its specific pH. Each zone contains highly concentrated solute, often near saturation level, and is separated from the neighbouring zone by a narrow strip called a mixing zone, which contains a mixture of impurities. Related Term - Counter-current chromatography: https://goldbook.iupac.org//terms/view/09887 Source - PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 205 (https://doi.org/10.1515/pac-2017-0111) Other Outputs - html: https://goldbook.iupac.org/terms/view/09947/html - json: https://goldbook.iupac.org/terms/view/09947/json - xml: https://goldbook.iupac.org/terms/view/09947/xml Citation: Citation: 'pH-zone-refining counter-current chromatography' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09947 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-04-18T06:27:30+00:00