{"term":{"id":"09944","title":"high-speed counter-current chromatography","longtitle":"IUPAC Gold Book - high-speed counter-current chromatography","doi":"10.1351\/goldbook.09944","code":"09944","status":"current","initialism":"<em>initialism<\/em>: HSCCC","definitions":[{"id":1,"text":"Counter-current chromatography system using a multilayer coil separation column, which undergoes a type-J synchronous planetary motion (see figure).Type-J planetary motion of a multilayer coil separation column. The column holder rotates about its own axis and revolves around the centrifuge axis at the same angular velocity (ω) in the same direction. This planetary motion prevents twisting of the bundle of flow tubes, allowing continuous elution through a rotating column without risk of leakage and contamination.","notes":{"1":"The method covers analytical (microgram) to preparative (\\(\\pu{10 g}\\)) scale separations usually in a few hours at a high partition efficiency up to a few thousand theoretical plates (see number of theoretical plates)."},"links":[{"term":"Counter-current chromatography","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/09887"}],"sources":["PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 203 (https:\/\/doi.org\/10.1515\/pac-2017-0111)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/09944\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/09944\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/09944\/plain"},"citation":"Citation: 'high-speed counter-current chromatography' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.09944","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-04-21T09:07:58+00:00"}}