{"term":{"id":"09938","title":"sedimentation field-flow fractionation","longtitle":"IUPAC Gold Book - sedimentation field-flow fractionation","doi":"10.1351\/goldbook.09938","code":"09938","status":"current","initialism":"<em>initialism<\/em>: SdFFF","definitions":[{"id":1,"text":"Field-flow fractionation in which the physical force field is a centrifugal force field. ","notes":{"1":"SdFFF is performed in a circular flat channel inserted inside a centrifugal basket.","2":"SdFFF can be applied to a wide range of colloidal and micron size particles and is a powerful method for cell separations, including industrial carbon blacks, silica nanoparticles, silver and gold nano-particles, aquatic sediments, aerosols, and latex beads.","3":"SdFFF can be successfully applied to the fractionation and characterization (sizing) of submicron particles, starting from about \\(\\pu{5 nm}\\), but this limit depends on the particle density, as the separation is based on the buoyant mass of the particles.","4":"SdFFF can operate in both the Brownian field-flow fractionation (BFFF) and hyperlayer field-flow fractionation (HyFFF) modes and caution must be exercised if samples span the Brownian-hyperlayer transition point of about \\(\\pu{1 \\upmu m}\\), as this can lead to separated fractions containing two particle sizes, smaller particles separated by Brownian mode and larger particles separated by hyperlayer mode."},"links":[{"term":"Brownian field-flow fractionation","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/09932"},{"term":"Field-flow fractionation","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/09934"},{"term":"hyperlayer field-flow fractionation","url":"https:\/\/goldbook.iupac.org\/\/terms\/view\/09937"}],"sources":["PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 222 (https:\/\/doi.org\/10.1515\/pac-2017-0111)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/09938\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/09938\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/09938\/plain"},"citation":"Citation: 'sedimentation field-flow fractionation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.09938","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-07-25T12:25:32+00:00"}}