<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>09887</id>
  <title>countercurrent chromatography</title>
  <longtitle>IUPAC Gold Book - countercurrent chromatography</longtitle>
  <doi>10.1351/goldbook.09887</doi>
  <code>09887</code>
  <status>current</status>
  <initialism><em>initialism</em>: CCC</initialism>
  <definitions>
    <item>
      <id>1</id>
      <text>Partition chromatography which uses two immiscible liquid phases and no solid support. One liquid acts as the stationary phase and the other as the mobile phase. </text>
      <notes>
        <item>The method employs a variety of systems using either gravity or centrifugal force to retain the stationary phase in the column.</item>
        <item>The method allows continuous elution of the mobile phase and on-line monitoring of the effluent.</item>
      </notes>
      <sources>
        <item>PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 186 (https://doi.org/10.1515/pac-2017-0111)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/09887/html</html>
    <json>https://goldbook.iupac.org/terms/view/09887/json</json>
    <plain>https://goldbook.iupac.org/terms/view/09887/plain</plain>
  </altoutputs>
  <citation>Citation: 'countercurrent chromatography' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09887</citation>
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  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-04-18T07:58:11+00:00</accessed>
</term>
