non-specific binding

in DNA-protein interactions
https://doi.org/10.1351/goldbook.09876

Binding of a protein to deoxyribonucleic acid (DNA) independent of the nucleotide sequence or the conformation of the DNA, often with a strong contribution of electrostatic interaction between the negatively charged sugar-phosphate backbone of the DNA and basic amino acid residues of the protein.

Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1185 [Terms] [Paper]
Citation: 'non-specific binding' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09876 RIS BibTex EndNote
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