Title: intramolecular interactions
Long Title: IUPAC Gold Book - intramolecular interactions
DOI: 10.1351/goldbook.09874
Status: current

Definition
Interactions between (neighbouring or distant) segments within the same biomolecule chain (e.g. base pairing in hairpin or monomolecular tetraplex structures of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), the interactions stabilizing the secondary or tertiary structures of proteins, etc.).

Related Terms
- biomolecule: https://goldbook.iupac.org//terms/view/09633
- tertiary: https://goldbook.iupac.org//terms/view/09785

Source
- PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1185 (https://doi.org/10.1515/pac-2016-1120)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/09874/html
- json: https://goldbook.iupac.org/terms/view/09874/json
- xml: https://goldbook.iupac.org/terms/view/09874/xml

Citation: Citation: 'intramolecular interactions' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09874
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-30T15:57:54+00:00