Changes in the lipid molecules composition after completion of their biosynthesis.
Notes: - In glycerophospholipids, remodelling includes changes in the composition of fatty acids (for example by acyl chain exchange catalysed by transacylases) or the introduction of unsaturated double bonds (catalysed by desaturases), or by the synthesis of new lipid species or degradation of existing ones. In phosphoinositides, it can involve phosphorylation/dephosphorylation processes.
- Lipid remodelling is important for the adaptation of biological membranes to changing environmental conditions and physiological demands.
Source:
PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1178 (https://doi.org/10.1515/pac-2016-1120)