Synthetic deoxyribonucleic acid (DNA) mimic, which contains 2-aminoethylglycine linkages instead of the negatively charged phosphodiesteric backbone of oligonucleotides.
Note: The PNA probes are particularly convenient for the detection of single-base
mismatches (point mutations, SNPs), because the stability of DNA-PNA duplexes is strongly influenced by a single-base mismatch.
Source:
PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1150 (https://doi.org/10.1515/pac-2016-1120)