nucleobase lesion

https://doi.org/10.1351/goldbook.09711

Product of chemical modification of a nucleobase.

Example: Products of oxidation (e.g. 8-oxoguanine), alkylation (e.g. O6-alkyl guanine), or deamination (e.g. uracil as a product of cytosine deamination).
See also: damage to DNA
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1149 [Terms] [Paper]
Citation: 'nucleobase lesion' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09711 RIS BibTex EndNote
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