Immunoreactivity of an antiserum with its designated antigen.
Note: In practice, true monospecificity to naturally occurring antigens does not occur in antisera produced by the immunization of the intact animal. An attempt is made to reduce the level of unwanted specificities below that which will interfere with the intended use of a particular immunochemical test.
Example: Reaction of an antiserum with antihuman \(\ce{IgG}\).
See also: immunochemical specificity
Source:
PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1142 (https://doi.org/10.1515/pac-2016-1120)