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<term>
  <id>09662</id>
  <title>agglutination inhibition</title>
  <longtitle>IUPAC Gold Book - agglutination inhibition</longtitle>
  <doi>10.1351/goldbook.09662</doi>
  <code>09662</code>
  <status>current</status>
  <definitions>
    <item>
      <id>1</id>
      <text>Type of agglutination in which particulate and soluble antigen compete for soluble antibody.</text>
      <notes>
        <item>Typically, it is soluble antigen in the test medium which reacts first with the soluble antibody, inhibiting the agglutination of indicator particles. With viral hemagglutination inhibition assays, host antibodies resulting from a specific infection are the most common forms of agglutination inhibition assays. In this case, viral-specific antibodies block the sites on the virus that agglutinate erythrocytes.</item>
      </notes>
      <sources>
        <item>PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1135 (https://doi.org/10.1515/pac-2016-1120)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/09662/html</html>
    <json>https://goldbook.iupac.org/terms/view/09662/json</json>
    <plain>https://goldbook.iupac.org/terms/view/09662/plain</plain>
  </altoutputs>
  <citation>Citation: 'agglutination inhibition' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09662</citation>
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  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-06-29T13:18:16+00:00</accessed>
</term>
