Title: agglutination inhibition
Long Title: IUPAC Gold Book - agglutination inhibition
DOI: 10.1351/goldbook.09662
Status: current

Definition
Type of agglutination in which particulate and soluble antigen compete for soluble antibody.

Note
Typically, it is soluble antigen in the test medium which reacts first with the soluble antibody, inhibiting the agglutination of indicator particles. With viral hemagglutination inhibition assays, host antibodies resulting from a specific infection are the most common forms of agglutination inhibition assays. In this case, viral-specific antibodies block the sites on the virus that agglutinate erythrocytes.

Source
- PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1135 (https://doi.org/10.1515/pac-2016-1120)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/09662/html
- json: https://goldbook.iupac.org/terms/view/09662/json
- xml: https://goldbook.iupac.org/terms/view/09662/xml

Citation: Citation: 'agglutination inhibition' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09662
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Accessed: 2026-06-29T13:22:56+00:00