matrix-assisted laser desorption electrospray ionization mass spectrometry

acronym: MALDESI
https://doi.org/10.1351/goldbook.09188
Measurement method in which a mass spectrometer is used to measure the ratio of mass to charge and the abundance of ionized entities from a sample that has been mixed with a matrix whose role is enhancing the ion yield produced by laser ablation and electrospray ionization.
Notes:
  1. The matrix, e.g. glycerol, allows efficient absorption of the laser energy and assists the desorption of the analyte molecules in the ejected charged droplets.
  2. Both positive and negative ions are observed.
See also: electrospray laser desorption ionization mass spectrometry, desorption atmospheric pressure photoionization, laser ablation electrospray ionization, desorption electrospray ionization, extractive electrospray ionization
Source:
PAC, 2020, 92, 1781. 'Glossary of methods and terms used in surface chemical analysis (IUPAC Recommendations 2020)' on page 1788 (https://doi.org/10.1515/pac-2019-0404)