08295 IUPAC Gold Book - two-dimensional correlation spectroscopy 10.1351/goldbook.08295 08295 current synonym: 2-D correlation spectroscopy 1 Measurement principle of spectroscopy in which spectra are recorded at different magnitudes of an applied external perturbation of the sample and are processed to yield a 2-D correlation spectrum. The external perturbation may be time dependent (chemical reactions, physical relaxation processes), or static (temperature change, concentration change). Correlation spectroscopy is used in infrared spectroscopy, nuclear magnetic resonance spectroscopy (COSY, TOCSY), fluorescence spectroscopy and others. 2-D correlation spectrum https://goldbook.iupac.org//terms/view/08296 COSY https://goldbook.iupac.org//terms/view/08323 TOCSY https://goldbook.iupac.org//terms/view/08435 fluorescence spectroscopy https://goldbook.iupac.org//terms/view/08454 infrared spectroscopy https://goldbook.iupac.org//terms/view/08618 nuclear magnetic resonance spectroscopy https://goldbook.iupac.org//terms/view/08218 PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 677 (https://doi.org/10.1515/pac-2019-0203) https://goldbook.iupac.org/terms/view/08295/html https://goldbook.iupac.org/terms/view/08295/json https://goldbook.iupac.org/terms/view/08295/plain Citation: 'two-dimensional correlation spectroscopy' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08295 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-27T22:13:51+00:00