Structural characteristic rendering a molecule chiral.
Examples: Four different substituents on a carbon atom (chirality center), conformational helix, and chiral axis (as in allenes \(\ce{XCH=C=CHX}\)).
Source:
PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 386 (https://doi.org/10.1515/pac-2018-1010)